This systematic review seeks to identify studies that examine the level of awareness, attitudes, and practices regarding breast cancer in adolescents and young adults, including their engagement in self-examination. The publications were retrieved from the PUBMED and SCOPUS databases in accordance with the 2020 guidelines for systematic reviews and meta-analyses (PRISMA). The research should be innovative and investigate the understanding and beliefs surrounding self-examination and the prevention of breast cancer among teenagers and young individuals who have not previously been diagnosed with or experienced breast cancer. The publications should be released in the English language between the years 2018 and 2023. According to the criteria outlined in the systematic review, a total of 14 studies were ultimately selected. Out of these, 4 studies focused on students, while the remaining research targeted undergraduate students. Adolescents and young adults had insufficient information of breast cancer prevention and self-examination. Additionally, more than 70% of young individuals expressed a desire to enhance their understanding about breast cancer. The papers emphasize the necessity of creating and executing health promotion initiatives to enhance the understanding and awareness of breast cancer among adolescents and young adults. This is crucial since breast cancer continues to be a significant concern in public health.