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Progress in Medical Sciences ISSN: 2577 - 2996
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Progress in Medical Sciences. 2021; 5(1):(49-110)
doi: doi.org/10.47363/PMS/2021(5)139


A Study of Vitamin D Status in Type 2 Diabetes Mellitus and Association of Vitamin D Levels with Glycemic Control

Fahmida Khatoon*, Shimaa Mohammed Hasnin Aboelnaga, Abdulsalam Al- Mhwes, Bashir Ahmed and Zahid Balouch

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Abstract
Diabetes mellitus is a group of metabolic disorders, characterized by chronic hyperglycemia due to relative or absolute deficiency of insulin. There can be a defect in insulin secretion, or its action (insulin resistance) or both. Diabetes mellitus (DM) is a worldwide health problem with rising prevalence, which seems due to change in life style, increasing obesity rates and aging of the population. Osteopenia and bone fragility is one of the problems faced by many diabetics without the nature of cause of either residual insulin secretion or high insulin requirement. Studies also show that patients with type 2 diabetes (T2DM) have an increased risk of hip and vertebral fracture, thus hinting the link between the two distinct pathologies. Aim of this study is to find out the association between Vitamin D levels with glycemic Control and to measure the vitamin Levels in Diabetes Patients. 

Conclusion: There is Negative association between Vitamin D and glycemic control. 

Materials & Methods: This Cross sectional study was conducted in the Hail region, KSA, during the period of 1st January 2018 to 21st March 2019. Total 210 study patients aged 18– 60 years; their Vitamin D levels were estimated and their socio-demographics data were collected regarding nationality, femininity, oldness, marital status, educational level, and occupation and analyze by SPSS 17. 

Result: Only 0.5 percent of the total sample was Vitamin D sufficient, while 37.1 percent was insufficient. Majority i.e. 62.4 % had deficiency of vitamin D. It can be observed that majority of patients i.e. 53.8 % had diabetes for 5-10 years. Only 9 patients out of a total of 210 had diabetes for more than 15 years. 

Conclusion: levels are Vitamin D levels in Diabetic patients are found to be low in Diabetic patients. Negative association is present between HbA1c levels and derangements in serum Vitamin D.