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Progress in Medical Sciences ISSN: 2577 - 2996

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Progress in Medical Sciences. 3021; 5(1):(43-113)

An Atypical Presentation of Legionnaire’s Disease

Zohra R. Malik* and Zareen Razaq

The multisystem involvement in Legionnaires' disease commonly includes the pulmonary, gastrointestinal tract, renal and neurological manifestations, but the mechanism of disease has not been defined except for the pulmonary system. Circulating toxins are the most likely culprit. We describe a nonfatal case of Legionnaires' disease that had seizures at presentation. The patient was a chronic alcoholic and a very remote history of seizures, the last seizure being 20 years ago. So at the time of presentation, we had to determine whether the seizure was due to withdrawal from substance abuse, was a regular tonic-clonic seizure that the patient was diagnosed with many years ago, or was it a manifestation of infection. An immunologic mechanism is mostly responsible for the extrapulmonary manifestations of Legionnaires' disease.