Infection of Aspergillous and Mucormycosis in Maxillary Region of a Woman with Diabetes After Covid19, A Case Report
Case Presentation: The patient was a 36-year-old woman with a history of uncontrolled diabetes mellitus who developed Covid 19, 5 months ago. And after a month of taking corticosteroids, she suffered from severe pain and swelling, along with necrosis and secretion of pus and loose teeth in the alveolar, palatal, and part of the masculine butters. Simultaneous presence of Aspergillus and Mucormycosis was reported after sampling and culture. Immediately after controlling the patient's glycemia and initiating Amphotericin and Clindamycin at the same time, the patient underwent infrastructural maxillectomy, including removal of the bone and mucosa of the alveolar, palatal region, part of the maxillary buttress on both sides, nasal septum, nasal floor, nasal mucosa and sinuses along the walls. Both sinuses were anteriorly, laterally, debridement, curettage, and washed with amphotericin. Injection of amphotericin continued for up to two months, and after two endoscopic biopsies and negative margins, both drugs were discontinued. And the patient is controlling for follow-up.
Conclusion: Due to the fatal fungal infection of Mucormycosis and Aspergillus and the extensive
involvement of the maxilla, prompt and extensive treatment can effectively help improve the disease. And
long-term follow-up and control of the patient's sugar accelerates the healing process.