This comprehensive research paper explores the application of Python-based predictive maintenance techniques in the medical equipment industry. By harnessing Python's robust data analysis and machine learning capabilities, healthcare providers and medical device manufacturers can significantly enhance equipment reliability, reduce downtime, and improve patient care. This study examines the implementation of predictive maintenance models, data processing techniques, and integration with Internet of Things (IoT) systems to create a holistic solution for medical equipment maintenance. The paper also addresses cybersecurity considerations and presents case studies demonstrating the effectiveness of Python-based predictive maintenance in real-world healthcare settings.